Table 1 |
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NIRS variables at end point between placebo and loratadine during +Gz exposure with GOR and ROR. |
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GOR |
ROR |
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|
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NIRS Variable |
Relaxed |
Straining |
Straining |
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Placebo |
Loratadine |
Placebo |
Loratadine |
Placebo |
Loratadine |
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|
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ΔO2Hb (μmol·L-1) |
-10.5 ± 5.6 |
-11.1 ± 5.7 |
-17.4 ± 8.1 |
-16.9 ± 7.4 |
-14.7 ± 7.2 |
-15.0 ± 6.4 |
|
ΔHHb (μmol·L-1) |
0.5 ± 2.4 |
-0.1 ± 3.4 |
2.8 ± 1.2 |
1.4 ± 4.6 |
0.7 ± 3.0 |
1.9 ± 3.7 |
|
ΔcHb (μmol·L-1) |
-11.3 ± 6.8 |
-12.8 ± 8.6 |
-13.2 ± 6.8 |
-15.5 ± 12.6 |
-13.6 ± 7.0 |
-12.0 ± 7.6 |
|
TOI% |
67.6 ± 4.5 |
70.2 ± 6.4 |
64.8 ± 3.7 |
67.2 ± 6.9 |
63.5 ± 4.8 |
66.3 ± 5.7 |
|
Baseline |
72.4 ± 4.7 |
73.6 ± 5.1 |
72.2 ± 4.9 |
73.7 ± 4.7 |
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ΔTOI% |
-4.8 ± 2.5 |
-3.3 ± 3.2 |
-7.6 ± 2.2 |
-6.4 ± 4.0 |
-8.8 ± 1.5 |
-7.4 ± 3.1 |
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|
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Values are means ± standard deviation. NIRS: near-infrared spectroscopy, GOR: gradual onset run, ROR: rapid onset run, O2Hb: oxygenated hemoglobin, HHb: deoxygenated hemoglobin, cHb: O2Hb + HHb, TOI: tissue oxygenation index, Δ: change. |
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Onozawa et al. Dynamic Medicine 2008 7:3 doi:10.1186/1476-5918-7-3 |
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