Table 1

Outcome measures for individuals with CFS alone; CFS-MCS; CFS-FM; or CFS-MCS-FM

Outcome Measure
CFS alone (n = 50)
CFS-MCS (n = 27)
CFS-FM (n = 18)
CFS-MCS-FM (n = 19)

Mean (Standard Deviation)
MOS-SF-36
     Physical Functioning
53.61 (25.05)a
42.50 (19.66)
40.56 (23.69)
32.89 (19.95)a
     Role-Physical
4.69 (12.27)
3.85 (11.60)
4.17 (12.86)
3.95 (12.54)
     Bodily Pain
49.83 (21.88)a,c
40.62 (21.63)b
30.00 (13.18)c
21.58 (18.60)a,b
     General Health
36.65 (16.74)a
28.75 (15.94)
38.54 (16.62)b
19.95 (32.24)a,b
     Vitality
20.73 (15.98)
15.19 (12.84)
19.72 (16.31)
11.32 (9.84)
     Social Functioning
46.09 (25.15)a
30.29 (21.84)a
47.22 (23.70)
30.26 (19.68)
     Role-Emotional
56.74 (45.00)
47.44 (45.39)
42.59 (35.80)
57.89 (41.34)
     Mental Health
67.08 (16.30)
55.85 (19.35)
66.22 (14.79)
62.11 (18.10)
Brief COPE
     Self Distraction
2.30 (0.87)a,b
2.91 (0.81)b
2.89 (0.88)
3.18 (0.65)a
     Active Coping
2.97 (0.84)
3.15 (0.83)
3.28 (0.73)
3.10 (0.88)
     Denial
1.41 (0.85)
1.28 (0.59)
1.25 (0.35)
1.32 (0.61)
     Substance Use
1.15 (0.47)
1.22 (0.63)
1.53 (0.98)
1.24 (0.42)
     Emotional Support
2.40 (0.95)
2.17 (0.91)
2.56 (0.97)
2.29 (0.85)
     Instrumental Support
2.32 (0.96)
2.61 (0.93)
2.78 (0.75)
2.66 (0.99)
     Behavioral Disengagement
1.33 (0.51)
1.27 (0.38)
1.47 (0.44)
1.47 (0.94)
     Venting
1.93 (0.63)
2.09 (0.77)
2.39 (0.65)
2.11 (.077)
     Positive Reframing
2.20 (1.06)
2.28 (0.94)
2.75 (0.96)
2.53 (1.05)
     Planning
2.97 (0.97)
3.00 (0.98)
3.00 (0.86)
3.03 (0.86)
     Humor
1.68 (0.79)a
1.78 (0.87)
2.39 (1.20)a
1.79 (0.77)
     Acceptance
2.95 (0.88)
2.81 (0.83)
2.94 (0.75)
2.95 (0.80)
     Religion
2.41 (1.01)
2.44 (0.97)
2.31 (1.06)
2.47 (1.05)
     Self Blame
1.69 (0.87)
1.74 (0.75)
2.00 (0.77)
1.92 (0.79)
Beck Depression Inventory
16.47 (8.61)a
20.88 (9.64)
18.50 (9.54)
23.93 (11.43)a
Fatigue Severity Scale
5.98 (0.68)
6.35 (0.66)a
5.70 (1.22)a
6.30 (0.53)
Pittsburgh Sleep Quality Index
7.26 (2.53)a
8.69 (2.20)
8.94 (2.10)
8.95 (2.39)a
Brief Pain Inventory
     Interference
2.83 (2.52)a,c,d
4.56 (2.78)b,c
5.36 (1.96)d
6.80 (2.33)a,b
     Severity
3.03 (2.06)a,c
4.06 (2.02)b
4.86 (1.40)c
6.10 (2.04)a,b
Symptoms
     Sore Throat
23.50 (26.61)
29.48 (26.97)
20.56 (26.40)
24.84 (28.82)
     Tender Lymph Nodes
25.75 (30.36)
23.40 (26.33)
27.50 (33.79)
32.00 (27.92)
     Muscle Pain
50.52 (28.34)a,b
60.76 (28.22)
72.92 (22.56)b
78.42 (24.97)a
     Joint Pain
31.85 (33.25)a,c
46.04 (35.95)b
63.06 (32.18)c
75.50 (24.54)a,b
     Impaired Memory
62.96 (25.22)
59.63 (23.82)
65.14 (25.53)
68.94 (22.65)
     Unrefreshing Sleep
76.89 (18.89)
75.19 (25.43)
89.67 (10.86)
87.03 (14.46)
     Post-Exertional Malaise
73.27 (17.84)
75.19 (19.16)
74.86 (23.74)
82.36 (14.10)
     Headaches
42.91 (33.39)a
56.87 (30.50)
55.00 (31.44)
74.03 (24.39)a
Six Minute Walk Test
     Distance Walked (feet)
1419.47 (312.17)
1728.08 (2387.62)
1304.28 (356.492)
1221.39 (239.23)
     Average RPE
9.85 (2.24)a
10.56 (2.08)
11.37 (2.76)
11.78 (2.42)a
Sit and Reach (inches)
13.48 (3.54)
13.16 (4.49)
14.55 (4.24)
13.40 (3.77)
Hand Grip (pounds)
     Right
64.45 (24.67)
61.57 (21.21)
64.19 (21.87)
52.28 (15.34)
     Left
60.04 (22.71)
58.63 (17.90)
58.72 (20.71)
48.07 (17.21)
Actigraphy Mean
161.35 (58.55)
145.74 (58.13)
167.23 (48.51)
149.78 (63.12)
Lifetime Axis I Diagnosis %
29 (58.0%)
17 (63.0%)
12 (66.7%)
13 (68.4%)
Current Axis I Diagnosis %
19 (38.0%)
8 (29.6%)
9 (50.0%)
8 (42.1%)

Similar letters across diagnostic groups significantly differ at the p < .05 level.

Brown and Jason Dynamic Medicine 2007 6:9   doi:10.1186/1476-5918-6-9